Ache reliever acetaminophen linked to larger threat of autism, ADHD: research

Researchers in Spain uncovered information that means a possible hyperlink between prenatal publicity to the frequent pain-relieving drug acetaminophen and elevated threat for larger situations of autism and attention-deficit/hyperactivity dysfunction, based on the outcomes of a research printed Friday.

The research, printed European Journal of Epidemiology, based mostly its findings on an evaluation of 73,881 mother-child pairs in Europe. 

Youngsters who have been prenatally uncovered to paracetamol, often known as acetaminophen, have been discovered to be 19% extra more likely to have developed Autism Spectrum Situations (ASC) and 21% extra more likely to have developed ADHD than youngsters who weren’t uncovered.

“These outcomes replicate earlier work and help offering clear info to pregnant girls and their companions about potential long-term dangers of acetaminophen use,” researchers on the College of Barcelona mentioned.

The researchers famous the research’s findings ought to be “interpreted with warning” and never taken as definitive proof of a hyperlink. The research discovered “no affiliation” between postnatal publicity to acetaminophen and ASC signs, based on a press launch from the Barcelona Institute for World Well being.


An estimated 46% to 56% of pregnant girls take acetaminophen in some unspecified time in the future throughout their being pregnant, based on the institute.

“Contemplating all evidences on acetaminophen use and neurodevelopment, we agree with earlier suggestions indicating that whereas acetaminophen shouldn’t be suppressed in pregnant girls or youngsters, it ought to be used solely when essential,” the researchers added.

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